The process decreases with age, and great lines and lines and wrinkles begin to appear. The movement of facial muscles causes wrinkles on the forehead also. Wrinkles are caused by exposure to the sun and dehydration also. There are two layers in the skin, epidermis and dermis. Lack of moisture causes fine lines in skin’s surface area. Collagen and break down to trigger sagging in the skin elastin, eventually turning into wrinkles. Wrinkles are caused by free radicals, exposure to sunshine, hormonal imbalance, muscle use and gravity.When physicians order an infusion of normal saline, Hartmann alternative, or 20 % albumin, these liquids bypass the gut, overrule the kidney sometimes, and reach into the deepest intracellular and interstitial crevices of the physical body. Clinicians owe it to patients to get intravenous liquid administration right. .. Childhood abuse increases threat of type 2 diabetes in women: Study A fresh study of nearly 70,000 women found a clear association between abuse in childhood and adolescence and the chance of type 2 diabetes in adult women. Very much, although not all, of this association is explained by the greater weight gain of ladies with a past background of abuse, said lead study author Janet Rich-Edwards.