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Improving immune response to vaccinations: Role of aluminium adjuvants An imminent publication in Tendencies in Immunology , hepatitis, polio, tetanus, diptheria and seasonal flu amongst numerous others. Regardless of the widespread usage of aluminium-structured adjuvants there is quite little knowledge of how they really work. A recently available flurry of analysis papers purported to describe their mode of actions ( though it all quickly became crystal clear that the tale was even now significantly confused ( The Opinion content in the prestigious review journal provides explained the most likely mode of actions of aluminium adjuvants in the context of both bioinorganic chemistry and immunobiology of aluminium. It offers helped to describe why previous recommendations as how aluminium adjuvants function are probably not relevant to the clinically accepted aluminium adjuvants found in individual vaccination programmes.