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Civacir was well tolerated with no drug-related serious adverse events observed during the study. Hepatitis C virus remains the leading trigger for liver transplantation and recurrent HCV disease may be the most frequent reason behind graft loss. Avoidance of recurrence independent of genotype and severity of cirrhosis is extremely desirable because it simplifies post-LT management.. The data demonstrate that intravenous Civacir provided both peri – and post-LT helps prevent HCV-reinfection in sufferers who also received antiviral therapy before their transplant operation. Civacir can be a hepatitis C immune globulin produced from pooled plasma from hundreds of screened donors who’ve high antibody titers against HCV. In this trial, individuals received AVT before their LT and the ones in the energetic treatment groups received 16 infusions of Civacir in the peri – and instant post-LT period for 10 weeks.