The discovery increases the need to educate the public on the need for meningitis vaccinations in potential cochlear implant recipients. The study’s authors found that in such cases, cochlear implantation lowers the threshold necessary for pneumococcal baterial infection, the bacterium that triggers meningitis. The study’s authors stress that it remains their belief that the advantages of cochlear implants considerably exceed the chance of meningitis, which may be managed by vaccination and education efforts. Worldwide, 90 of the 60,000 people getting cochlear implant have been stricken with meningitis, drawing deep concern within the worldwide medical community. Previous study by the Centers for Disease Control and Avoidance determined that children who receive cochlear implants to counter hearing loss will develop meningitis..RNA sequencing of both single and clustered CTCs from breasts cancer patients identified several genes expressed at elevated levels in CTC clusters, one of which – a protein known as plakoglobin – also was overexpressed in the primary tumors of sufferers with reduced survival. Analysis of blood and tissue samples in one affected individual uncovered that plakoglobin was expressed in CTC clusters however, not single CTCs and in addition was expressed in some portions of both the main tumor and metastases. Plakoglobin is an element of two important structures involved in cell-to-cell adhesion, and the investigators discovered that suppressing its expression caused CTC clusters to break apart, reducing their metastatic potential, and also disrupted cell-to-cell get in touch with between breast cancer cells however, not normal breast cells.